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Tricyclic Antidepressant (TCA) Screen Test

This test checks for tricyclic antidepressants (TCAs) in your blood or urine. It can help your provider find the right dose, check for misuse, or diagnose an overdose.

What this test measures

This test measures whether tricyclic antidepressants (TCAs) are present in your blood or urine, and can also measure the amount of TCA.

What your results mean

Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.

Higher-than-normal results

If blood or urine test results show you have dangerously high levels of TCA, you will be treated immediately.

Frequently asked questions

What is a TCA screen?

It is a test that checks for tricyclic antidepressants (TCAs) in your blood or urine.

Why might I need this test?

To help your provider find the right dose, check for misuse, or diagnose an overdose.

What are some common TCAs?

Common TCAs include doxepin, nortriptyline, amitriptyline, imipramine, and desipramine.

What do the results mean?

Results show TCA levels in your blood or whether TCA is present in urine. Your provider may adjust your dose based on the results.

What happens if TCA levels are too high?

If levels are dangerously high, you will be treated immediately.

Sources

Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.