PTEN Genetic Test Test
A PTEN genetic test looks for changes in the PTEN gene, which can affect how your body controls cell growth. It helps find out if a gene change is linked to cancer or to inherited conditions like PTEN hamartoma tumor syndrome (PHTS).
What this test measures
A PTEN genetic test uses a sample of your blood or other body tissue to look for changes in a gene called PTEN. PTEN is a tumor suppressor gene that helps prevent or slow the growth of cells that may become tumors.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Frequently asked questions
What is a PTEN genetic test?
It is a test that looks for changes in the PTEN gene using a sample of your blood or other body tissue.
What does the PTEN gene do?
PTEN is a tumor suppressor gene that helps prevent cells from growing too quickly, repairs damaged DNA, and starts cell death in cells that can't be repaired.
What are acquired PTEN gene changes?
Acquired changes develop after birth and are not passed down from parents. They are commonly found in many cancers, including prostate, uterine, and some brain tumors.
What are inherited PTEN gene changes?
Inherited changes are present at birth and can be passed from parent to child. They can cause disorders like Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome, grouped as PTEN hamartoma tumor syndrome (PHTS).
What does a positive test for inherited PTEN changes mean?
It means you have PHTS, which raises your risk for certain cancers like breast, thyroid, and kidney cancer. It does not mean you have cancer, but your provider may recommend steps to reduce your risk.
Related lab tests
Sources
- MedlinePlus: PTEN Genetic Test — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.