Lipase Tests Test
A lipase test measures the level of lipase in your blood. High levels may indicate pancreatitis or other pancreatic diseases, while low levels may suggest permanent damage to the pancreas.
What this test measures
A lipase test measures the level of lipase in your blood. Lipase is a digestive enzyme that helps your body digest fats. Most lipase is made in the pancreas.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
A very high level of lipase is usually a sign of acute pancreatitis. Higher than normal levels may also be caused by pancreatic duct blockage, pancreatic cancer, chronic kidney disease, peptic ulcer, gallbladder disease, intestinal blockage, diabetes, salivary gland disorders, or alcohol use disorder.
Lower-than-normal results
Low levels of lipase may be a sign of permanent damage to cells in your pancreas that make lipase. This may happen in chronic diseases such as cystic fibrosis and chronic pancreatitis.
Frequently asked questions
What is a lipase test?
A lipase test measures the level of lipase in your blood. Lipase is a digestive enzyme that helps your body digest fats.
Why might I need a lipase test?
It may be used to help diagnose pancreatic diseases like acute pancreatitis, check if treatment for pancreatic diseases is working, or help diagnose conditions like cystic fibrosis, Crohn's disease, or celiac disease.
What does a high lipase level mean?
A very high level is usually a sign of acute pancreatitis. Higher levels can also be caused by pancreatic cancer, kidney disease, gallbladder disease, or other conditions.
What does a low lipase level mean?
Low levels may indicate permanent damage to the cells in your pancreas that make lipase, which can happen in chronic diseases like cystic fibrosis or chronic pancreatitis.
Can medicines affect lipase levels?
Yes, many medicines including codeine, diuretics, certain cholesterol medicines, and birth control pills can affect your lipase levels.
Related lab tests
Sources
- MedlinePlus: Lipase Tests — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.