CCP Antibody Test Test
A CCP antibody test looks for proteins in your blood that attack your joints. A positive result may mean you have rheumatoid arthritis.
What this test measures
This test measures CCP (cyclic citrullinated peptide) antibodies in your blood. These are autoantibodies that mistakenly attack healthy joint tissues.
What your results mean
Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.
Higher-than-normal results
A positive result means CCP antibodies were found. If you also have symptoms of rheumatoid arthritis, it may mean you have the disease. In some cases, it could mean early-stage rheumatoid arthritis or other conditions like lupus or chronic lung disease.
Lower-than-normal results
A negative result means no CCP antibodies were found. If you also have a negative RF test, it means you are less likely to have rheumatoid arthritis, but more tests may be needed.
Frequently asked questions
What is a CCP antibody test?
It is a blood test that looks for CCP antibodies, which are proteins that attack your joints.
Why is this test done?
It helps diagnose or rule out rheumatoid arthritis.
What does a positive result mean?
It means CCP antibodies were found. If you have symptoms, it likely means rheumatoid arthritis.
What does a negative result mean?
It means no CCP antibodies were found. You are less likely to have rheumatoid arthritis.
Is this test done with other tests?
Yes, it is often done with a rheumatoid factor (RF) test for a more accurate diagnosis.
Related lab tests
Sources
- MedlinePlus: CCP Antibody Test — NIH MedlinePlus
Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.