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Calprotectin Stool Test Test

This test measures calprotectin in your stool to check for inflammation in your intestines. High levels suggest inflammation, which may be due to conditions like inflammatory bowel disease (IBD).

What this test measures

A calprotectin stool test measures a protein called calprotectin in a sample of your stool. It is used to check for inflammation (swelling and irritation) in your intestines.

What your results mean

Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.

Higher-than-normal results

High levels of calprotectin usually mean your intestines are inflamed. Very high levels are often linked to inflammatory bowel disease (IBD) or food poisoning from certain bacteria. Somewhat high levels may be linked to intestinal or colorectal cancer, celiac disease, certain bacterial infections like C. diff, taking NSAIDs, or treated IBD.

Lower-than-normal results

Normal or low levels of calprotectin usually mean your intestines are not inflamed, which suggests you do not have inflammatory bowel disease (IBD). Your symptoms are probably caused by a non-inflammatory condition.

Frequently asked questions

What is a calprotectin stool test?

It measures a protein called calprotectin in your stool to check for inflammation in your intestines.

Why is this test done?

It helps tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), and can check how severe IBD is or if treatment is working.

What do high levels mean?

High levels usually mean your intestines are inflamed. Very high levels are often linked to IBD or bacterial food poisoning.

What do normal levels mean?

Normal levels usually mean no inflammation, so your symptoms are likely from a non-inflammatory condition like IBS.

Can the test be wrong?

Yes, false negatives can happen, mostly in children, where inflammation is present but calprotectin levels are normal.

Related lab tests

Sources

Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.