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BRAF Genetic Test Test

A BRAF genetic test looks for changes in the BRAF gene that may be involved in cancer. The results help your healthcare provider choose the most effective treatment for your cancer.

What this test measures

A BRAF genetic test uses a sample of tumor tissue, bone marrow, or blood to look for changes (mutations) in the BRAF gene. The BRAF gene provides instructions for making a protein that controls cell growth. Certain changes can cause the protein to be too active, leading to uncontrolled cell growth and cancer.

What your results mean

Reference ranges vary by laboratory and by your age and sex. MedlinePlus does not publish a single normal range for this test — always read your result against the range printed on your own lab report and discuss it with your provider.

Higher-than-normal results

If you have cancer and your test shows a change in your BRAF gene, your provider may prescribe medicines that target the changed BRAF proteins. You may also need other treatments.

Lower-than-normal results

If you have cancer and your test shows no change in your BRAF gene, your provider will prescribe another type of treatment for your cancer.

Frequently asked questions

What is a BRAF genetic test?

It is a test that looks for changes in the BRAF gene using a sample of tumor tissue, bone marrow, or blood.

Why is the BRAF test done?

It is usually done to look for BRAF gene changes that may be involved in cancer and to help guide treatment decisions.

What does a positive BRAF test mean?

If you have cancer and the test finds a BRAF change, your provider may prescribe medicines that target the abnormal BRAF proteins.

Can I inherit a BRAF gene change?

Inherited changes are very rare, but they can increase your risk of cancer or cause genetic conditions present from birth.

Does a BRAF gene change mean I will get cancer?

No, it does not mean you will get cancer, but depending on the change, you may have a higher risk.

Sources

Last updated . Information is aggregated from official public sources and is not a substitute for professional medical care.